Specific Visualization of Glioma Cells in Living Low-Grade Tumor Tissue

Sven R. Kantelhardt, Wouter Caarls, Anthony H. B. de Vries, Guy M. Hagen, Thomas M. Jovin, Walter Schulz‐Schaeffer, Veit Rohde, Alf Giese, Donna J. Arndt‐Jovin

PLoS ONE · 2010 · 46 citations · 26 references

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Abstract

The ability of the targeted probes to clearly distinguish tumor cells in low-grade tumor biopsies, where no enhanced MRI image was obtained, demonstrates the great potential of the method. We propose that future application of specifically targeted fluorescent particles during surgery could allow intraoperative guidance for the removal of residual tumor cells from the resection cavity and thus increase patient survival.

References

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