Concepedia

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

Klaus Martin, Didier Trouche, Christian Hagemeier, Troels S. Sørensen, Nicholas B. La Thangue, Tony Kouzarides

Nature · 1995 · 458 citations · 23 references

DOI

Concepts

References

23

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

, , +10

Amplification of a gene encoding a p53-associated protein in human sarcomas

Jonathan D. Oliner, Kenneth W. Kinzler, Paul S. Meltzer et al. · Nature · 1992 · 2K citations · Full text

, , +12

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

Suzanne J. Baker, Sanford D. Markowitz, Eric R. Fearon et al. · Science · 1990 · 1.8K citations

, , +17

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner, Jennifer A. Pietenpol, Sam Thiagalingam et al. · Nature · 1993 · 1.5K citations

, , +16

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

D. Gale Johnson, James K. Schwarz, W. Douglas Cress et al. · Nature · 1993 · 953 citations

, , +15