Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer

Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions

M.T. Bardo, Ronald P. Hammer · Neuroscience · 1991 · 3.2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Quantitative autoradiographic localization of the D1 and D2 subtypes of dopamine receptors in rat brain

SJ Boyson, Paul McGonigle, P B Molinoff · Journal of Neuroscience · 1986 · 746 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Central D2-Dopamine Receptor Occupancy in Schizophrenic Patients Treated With Antipsychotic Drugs

Lars Farde · Archives of General Psychiatry · 1988 · 693 citations

Medicine, Pharmacology, Psychiatry +17

Specific in vitro and in vivo binding of 3H-raclopride a potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain

Christer Köhler, Håkan Hall, Sven Ove Ögren et al. · Biochemical Pharmacology · 1985 · 506 citations

Medicine, Neuroscience, Pharmacology +12

Antipsychotic Dosing in Preclinical Models Is Often Unrepresentative of the Clinical Condition: A Suggested Solution Based on in Vivo Occupancy

Shitij Kapur, Susan C. VanderSpek, Barbara A. Brownlee et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 478 citations

Medicine, Pharmacokinetics, Pharmacology +15