LPK-26, a novel κ-opioid receptor agonist with potent antinociceptive effects and low dependence potential

[3H]U-69593 a highly selective ligand for the opioid κ receptor

Robert A. Lahti, Mary M. Mickelson, John M. McCall et al. · European Journal of Pharmacology · 1985 · 446 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.

J A Clark, L Liu, MA Price et al. · Journal of Pharmacology and Experimental Therapeutics · 1989 · 339 citations

Medicine, Neuroscience, Pharmacology +17

Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors.

R. Suzanne Zukin, M Eghbali, David L. Olive et al. · Proceedings of the National Academy of Sciences · 1988 · 315 citations

Medicine, Neurobiology, Pharmacology +13

Properties of a selective kappa agonist, U-50,488H

Robert A. Lahti, Philip F. VonVoigtlander, Craig L. Barsuhn · Life Sciences · 1982 · 198 citations

Medicine, Pharmacology, Cell Signaling +8

Comparison of Pharmacological Activities of Three Distinct κ Ligands (Salvinorin A, TRK-820 and 3FLB) on κ Opioid Receptors in Vitro and Their Antipruritic and Antinociceptive Activities in Vivo

Yu‐Lin Wang, Kang Tang, Saadet Inan et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 193 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17