Concepedia

Molecular and functional characterization of drug-metabolizing enzymes and transporter expression in the novel spontaneously immortalized human hepatocyte line HC-04

Priscilla Lay Keng Lim, Calivarathan Latchoumycandane, Wei Chuen Mok, Yok Moi Khoo, How Sung Lee, Jetsumon Sattabongkot, Walter Beerheide, Seng Gee Lim, Theresa May Chin Tan, Urs A. Boelsterli

Toxicology in Vitro · 2007 · 34 citations · 50 references

DOI

Concepts

References

50

Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.

Marcel Kool, Marcel de Haas, George L. Scheffer et al. · PubMed · 1997 · 898 citations

, , +15

COMPARISON OF PRIMARY HUMAN HEPATOCYTES AND HEPATOMA CELL LINE HEPG2 WITH REGARD TO THEIR BIOTRANSFORMATION PROPERTIES

Stefan Wilkening, Frank Stahl, Augustinus Bader · Drug Metabolism and Disposition · 2003 · 771 citations

, , +17

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

Thomas Kronbach, Daniel Mathys, Makoto Umeno et al. · Molecular Pharmacology · 1989 · 535 citations

, , +15

c-Jun N-Terminal Kinase Plays a Major Role in Murine Acetaminophen Hepatotoxicity

Basuki Gunawan, Zhang‐Xu Liu, Derick Han et al. · Gastroenterology · 2006 · 476 citations · Full text

, , +16

Correlation of Gene Expression of Ten Drug Efflux Proteins of the ATP-Binding Cassette Transporter Family in Normal Human Jejunum and in Human Intestinal Epithelial Caco-2 Cell Monolayers

Jan Taipalensuu, Hans Törnblom, Greger Lindberg et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 444 citations

, , +13