Xenogeneic islet transplantation of microencapsulated porcine islets for therapy of type I diabetes: long-term normoglycemia in STZ-diabetic rats without immunosuppression

Clinical Outcomes and Insulin Secretion After Islet Transplantation With the Edmonton Protocol

Edmond A. Ryan, Jonathan R. T. Lakey, Ray V. Rajotte et al. · Diabetes · 2001 · 872 citations · Full text

Medicine, Endocrinology, Surgery +17

Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression.

Yuxiu Sun, Xiaochi Ma, David Zhou et al. · Journal of Clinical Investigation · 1996 · 453 citations · Full text

Medicine, Endocrinology, Surgery +15

Production of mitogen‐contamination free alginates with variable ratios of mannuronic acid to guluronic acid by free flow electrophoresis

U. Zimmermann, Gerd Klöck, K. Federlin et al. · Electrophoresis · 1992 · 201 citations

Engineering, Bioengineering, Immunology +14

A Method for the Mass Isolation of Islets From the Adult Pig Pancreas

Camillo Ricordi, EDWARD H. FINKE, Paul E. Lacy · Diabetes · 1986 · 170 citations

Medicine, Endocrinology, Physiology +9

Porcine Endogenous Retroviruses Inhibit Human Immune Cell Function: Risk for Xenotransplantation?

Stefan J. Tacke, Reinhard Kurth, Joachim Denner · Virology · 2000 · 101 citations

Life Sciences, Immunology, Molecular Biology +10