Evaluation of the human serum albumin column as a discovery screening tool for plasma protein binding

The Pharmacological Basis of Therapeutics

American Journal of Health-System Pharmacy · 1976 · 8.2K citations

Medicine, Pharmacology, Pharmacotherapy +10

Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes

R. Scott Obach · Drug Metabolism and Disposition · 1999 · 1.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Crossvalidation, Bootstrapping, and Partial Least Squares Compared with Multiple Regression in Conventional QSAR Studies

Richard D. Cramer, Jeffrey D. Bunce, David E. Patterson et al. · Quantitative Structure-Activity Relationships · 1988 · 840 citations

Pharmacy, Medicinal Chemistry, Drug Design +9

Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase

T. A. G. Noctor, Irving W. Wainer, David S. Hage · Journal of Chromatography B Biomedical Sciences and Applications · 1992 · 160 citations

Pharmacy, Biochemistry, Pharmacology +14

Use of a Human Serum Albumin-Based High-Performance Liquid Chromatography Chiral Stationary Phase for the Investigation of Protein Binding: Detection of the Allosteric Interaction between Warfarin and Benzodiazepine Binding Sites

Enrico Domenici, Carlo Bertucci, Piero Salvadori et al. · Journal of Pharmaceutical Sciences · 1991 · 127 citations

Pharmacy, Biochemistry, Pharmacology +16