Relationship between plasma and lymphocyte linoleate in multiple sclerosis.

Abstract

The linoleate level in total lipids was measured in lymphocytes from control subjects and patients with multiple sclerosis. A small but significant decrease was found in cases of multiple sclerosis. The percentage composition of lymphocyte fatty acids was determined in rats fed diets with various linoleate contents. There was a correlation between lymphocyte linoleate and plasma linoleate in both humans and rats.