A fluorescent test for the rheumatoid factor in blood

Abstract

Abstract A fluorescent test for the rheumatoid factor is described in which the buffy coat of blood is separated and treated with fluoresceinated aggregated F‐II of human gamma globulin. Fluorescence of the suspended leukocytes and platelets indicates the presence of the factor coated on the cell surfaces. Ninety per cent of patients with adult rheumatoid arthritis and 76 per cent with juvenile rheumatoid arthritis gave positive tests.