Reproducibility of the capsaicin‐induced dermal blood flow response as assessed by laser Doppler perfusion imaging

Abstract

Capsaicin induces a reproducible within-subject arm-to-arm increase in DBF. We provide a non-invasive pharmacodynamic model in humans to test antagonists of mediators involved in capsaicin-induced dermal vasodilation, including calcitonin gene-related peptide antagonists.