PLoS ONE · 2011 · 71 citations · 17 references
Life SciencesPlant BiologyPlant SciencesPlant BiochemistryPlant Hormone BiologyPlant PhysiologyPlant Growth RegulationPlant Hormone SignalingPlant HormonesSeed Germination InhibitionSeedling Growth SuppressionStrigolactone BiologyInhibitory Germination EffectsPlant Height ControlPlant Height ModificationRoot Exudate EffectsSeedling Growth InhibitorsStrigolactone BiosynthesisStrigolactone-mediated GerminationTriazole Chemistry
We previously discovered a lead compound for strigolactone (SL) biosynthesis inhibitors, TIS13 (2,2-dimethyl-7-phenoxy-4-(1H-1,2,4-triazol-1-yl)heptan-3-ol). Here, we carried out a structure-activity relationship study of TIS13 to discover more potent and specific SL biosynthesis inhibitor because TIS13 has a severe side effect at high concentrations, including retardation of the growth of rice seedlings. TIS108, a new TIS13 derivative, was found to be a more specific SL biosynthesis inhibitor than TIS13. Treatment of rice seedlings with TIS108 reduced SL levels in both roots and root exudates in a concentration-dependent manner and did not reduce plant height. In addition, root exudates of TIS108-treated rice seedlings stimulated Striga germination less than those of control plants. These results suggest that TIS108 has a potential to be applied in the control of root parasitic weeds germination.
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Strigolactone inhibition of shoot branching
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