PubMed · 2003 · 128 citations · 10 references
MedicineBiochemistryOncologyCancer PreventionCarcinogenesisClinical BiochemistryColorectal CancerCopper MetabolismOxidative Stress In CarcinogenesisAntioxidantsCeruloplasmin BiologyCopper BiomarkersEarly DiagnosisEnzymatic AntioxidantsNatural Antioxidants
Serum copper and ceruloplasmin levels were estimated in 20 patients each of prostate and colon cancer. Although copper to ceruloplasmin ratio was not significantly altered, copper and ceruloplasmin levels were increased significantly in the cancer patients as compared to controls. Trace elements and free radicals have been implicated in the etiology of cancer. Hence determination of specific antioxidants (like ceruloplasmin) and trace elements (like copper) may be of value in the early diagnosis of prostate and colon cancer.
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Carcinoembryonic antigen in breast cancer patients: Serum levels and disease progress
A. M. Steward, Daniel W. Nixon, Norman Zamcheck et al. · Cancer · 1974 · 207 citations · Full text