Structural and functional properties of lengsin, a pseudo-glutamine synthetase in the transparent human lens

Hsp70 and Hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

Paul J. Muchowski, Gregor Schaffar, Annie Sittler et al. · Proceedings of the National Academy of Sciences · 2000 · 673 citations

Life Sciences, Biochemistry, Molecular Biology +17

Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein

Stephen B. Willingham, Tiago F. Outeiro, Michael J. DeVit et al. · Science · 2003 · 427 citations

Life Sciences, Genetics, Molecular Biology +15

Mutation R120G in αB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

Michael P. Bova, Orna Yaron, Qingling Huang et al. · Proceedings of the National Academy of Sciences · 1999 · 371 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

[30] Lens α-crystallin: Chaperone-like properties

Joseph Horwitz, Qing-Ling Huang, Linlin Ding et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 1998 · 227 citations

Natural Sciences, Physics, Crystal Structure +6

Evolutionary Diversity of Vertebrate Small Heat Shock Proteins

Erik Franck, Ole Madsen, Teun van Rheede et al. · Journal of Molecular Evolution · 2004 · 196 citations

Life Sciences, Biology, Molecular Biology +11