Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Jeh-Ping Liu, Julie C. Baker, Archlbald S. Perkins et al. · Cell · 1993 · 2.9K citations

Life Sciences, Developmental Biology, Genetics +16

Agar suspension culture for the selective assay of cells transformed by polyoma virus

Ian Macpherson, Luc Montagnier · Virology · 1964 · 1.3K citations

Life Sciences, Cell Biology, Molecular Virology +9

Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor.

Christian Sell, Michele Rubini, R Rubin et al. · Proceedings of the National Academy of Sciences · 1993 · 556 citations

Life Sciences, Molecular Biology, Molecular Genetics +13

The IRS-signalling system: A network of docking proteins that mediate insulin action

Morris F. White · Molecular and Cellular Biochemistry · 1998 · 533 citations

Life Sciences, Biochemistry, Molecular Biology +14

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts.

Christian Sell, Guillaume Duménil, Catherine Deveaud et al. · Molecular and Cellular Biology · 1994 · 523 citations · Full text

Life Sciences, Genetics, Molecular Biology +15