Influence of Acetazolamide and CO ₂ on Extracranial Flow Volume and Intracranial Blood Flow Velocity

Abstract

These data show not only the expected increase of flow velocity in the middle cerebral artery but also suggest an increase in cross-sectional vessel diameter of 6% and 4% with CO2 and acetazolamide, respectively. It remains unresolved whether this observation is due to a direct effect of the drug on the vessel walls or is simply pressure dependent.