Concepedia

The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo

Natalia Edison, Dotan Zuri, Inbal Maniv, Bavat Bornstein, Tali Lev, Yossi Gottfried, Stav Kemeny, María García‐Fernández, Juliana Kagan, Sarit Larisch

Cell Death and Differentiation · 2011 · 55 citations · 31 references

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31

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

Honglin Li, Hong Zhu, Chi-jie Xu et al. · Cell · 1998 · 4.4K citations · Full text

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Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

, , +14

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

, , +17

Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

Anne M. Verhagen, Paul G. Ekert, Miha Pakusch et al. · Cell · 2000 · 2.3K citations · Full text

, , +14

X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen et al. · Nature · 1997 · 1.9K citations · Full text

, , +12