Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

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Multipotent cell lineages in early mouse development depend on SOX2 function

Ariel A. Avilion, Silvia K. Nicolis, Larysa Pevny et al. · Genes & Development · 2003 · 2.4K citations · Full text

Life Sciences, Developmental Biology, Genetics +17

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

Jiřina Bártková, Nousin Rezaei, Michalis Liontos et al. · Nature · 2006 · 2K citations

Medicine, Cancer Biology, Oncology +16

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese et al. · Nature · 2006 · 1.8K citations

Medicine, Molecular Biology, Oncology +16

SOX2 Functions to Maintain Neural Progenitor Identity

Victoria Graham, Jane Khudyakov, Larysa Pevny · Neuron · 2003 · 1.4K citations · Full text

Life Sciences, Developmental Biology, Genetics +14