Proximal HNF1 element is essential for the induction of human UDP-glucuronosyltransferase 1A1 by glucocorticoid receptor

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

Genetics, Cyp3a4 Gene, Mouse Pxr Reveals +18

The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome

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Functional domains of the human estrogen receptor

Vijay Kumar, Stephen Green, Gary Stack et al. · Cell · 1987 · 1.3K citations

Functional Domains, Signal Transduction, Hormonal Receptor +6

The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene

Tatsuya Sueyoshi, Takeshi Kawamoto, Igor N. Zelko et al. · Journal of Biological Chemistry · 1999 · 671 citations · Full text

Genetic variation in bilirubin UDP-glucuronosyltransferase gene promoter and Gilbert's syndrome

Gemma Monaghan, Máirín Ryan, Robert Hume et al. · The Lancet · 1996 · 588 citations

Allelic Variant, Genetic Disorder, Genetics +9