Concepedia

The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse

Pär Steneberg, Nir Rubins, Reut Bartoov-Shifman, Michael Walker, Helena Edlund

Cell Metabolism · 2005 · 414 citations · 55 references

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55

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

Akira Hirasawa, Keiko Tsumaya, Takeo Awaji et al. · Nature Medicine · 2004 · 1.5K citations

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Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

Yasuaki Itoh, Yuji Kawamata, Masataka Harada et al. · Nature · 2003 · 1.5K citations

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The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids

Celia P. Briscoe, Mohammad Tadayyon, John L. Andrews et al. · Journal of Biological Chemistry · 2003 · 1.1K citations · Full text

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Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes

Chenyu Zhang, György Baffy, Pascale Perret et al. · Cell · 2001 · 916 citations · Full text

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Liver Peroxisome Proliferator-activated Receptor γ Contributes to Hepatic Steatosis, Triglyceride Clearance, and Regulation of Body Fat Mass

Oksana Gavrilova, Martin Haluzı́k, Kimihiko Matsusue et al. · Journal of Biological Chemistry · 2003 · 766 citations · Full text

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