Helvetica Chimica Acta · 1966 · 28 citations · 10 references
Life SciencesBiochemistryChemistrySteroid BiochemistryRetrosynthetic AnalysisSteroid BiosynthesisSteroid Hormone BiochemistrySteroid StructureChirality In SteroidsConfigurational AnalysisConfigurational AssignmentEcdysteroid BiosynthesisSteroid Hormone Biosynthetic PathwaysSteroid Ring Conformation
Abstract Experiments towards a synthesis of ecdysone ( 1 ) ([22 R ]‐2β, 3β, 14, 22, 25‐pentahydroxy‐5β, 14α‐cholest‐7‐en‐6‐one) have led to 2β, 3β‐dihydroxy‐6‐keto‐5α‐steroids. These could be epimerized to the corresponding 5β‐series. The proposed configurational assignments are supported by physical data and chemical correlation.
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