Concepedia

Prenatal freeze lesioning produces epileptogenic focal cortical dysplasia

Kei‐ichiro Takase, Hiroshi Shigeto, Satoshi O. Suzuki, Hitoshi Kikuchi, Yasumasa Ohyagi, Jun‐ichi Kira

Epilepsia · 2008 · 37 citations · 24 references

DOI

Abstract

Prenatal freeze lesioning of the brain produces a severe neuronal migration disorder, closely mimicking human FCD. Our model suggests that FCD is associated with vulnerability to epilepsy, and may augment hippocampal epileptogenicity.

References

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