Hitoshi Kikuchi

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Koji Abe, Masashi Aoki, Shoji Tsuji et al. · The Lancet Neurology · 2017 · 900 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Neurological Disorder +6

Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis

Takaaki Ishizu, Manabu Osoegawa, Feng-Jun Mei et al. · Brain · 2005 · 331 citations · Full text

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

Hitoshi Kikuchi, Gabriele Almer, Satoshi Yamashita et al. · Proceedings of the National Academy of Sciences · 2006 · 311 citations · Full text

Molecular Biology, Cell Death, Redox Biology +19

Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease

Yasumasa Ohyagi, Hideaki Asahara, De-Hua Chui et al. · The FASEB Journal · 2004 · 277 citations

Apoptosis, Cell Death, Social Sciences +18

Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in Japanese

Tatsuomi Matsuoka, Takuya Matsushita, Yohei Kawano et al. · Brain · 2007 · 271 citations · Full text