Arylsulfonyl chlorides in the presence of N-methylimidazole as efficient condensing reagents in phosphotriester oligonucleotide synthesis

Use of arylsulfonyltriazoles for the synthesis of oligonucleotides by the triester approach

N. KATAGIRI, K. Itakura, Saran A. Narang · Journal of the American Chemical Society · 1975 · 123 citations

Natural Sciences, Chemistry, Bioorthogonal Chemistry +7

Simplifications in the synthesis of short oligonucleotide blocks

Chris A. Broka, Toyoharu Hozumi, René Arentzen et al. · Nucleic Acids Research · 1980 · 72 citations · Full text

Pharmacy, Chemical Biology, Molecular Biology +11

A study of the efficiency and the problem of sulfonation of several condensing reagents and their mechanisms for the chemical synthesis of deoxyoligoribonucleotides

Arun K. Seth, Ernest Jay · Nucleic Acids Research · 1980 · 66 citations · Full text

Natural Sciences, Biochemistry, Chemistry +6

Rotected deoxyribonucleoside-3′ aryl phosphodiesters as key intermediates in polynucleotide synthesis. Construction of an icosanucleotide analogous to the sequence at the ends of Rous sarcoma virus 35S RNA

G.R. Gough, Charles K. Singleton, H L Weith et al. · Nucleic Acids Research · 1979 · 61 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Synthesis of the human insulin gene. Part II. Further improvements in the modified phosphotriester method and the synthesis of seventeen deoxyribooligonucleotide fragments constituting human insulin chains B and mini-C DNA

Wing L. Sung, Hansen M. Hsiung, Roland Brousseau et al. · Nucleic Acids Research · 1979 · 29 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16