MAR characteristic motifs mediate episomal vector in CHO cells

Transcriptional silencing is associated with extensive methylation of the CMV promoter following adenoviral gene delivery to muscle

Alan R. Brooks, Richard N. Harkins, Peiyin Wang et al. · The Journal of Gene Medicine · 2004 · 372 citations

Life Sciences, Genetics, Molecular Genetics +16

A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells

Christoph Piechaczek, Christiane Fetzer, Armin Baiker et al. · Nucleic Acids Research · 1999 · 211 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

The Three-Dimensional Structure of Human Interphase Chromosomes Is Related to the Transcriptome Map

Sandra Goetze, Julio Mateos‐Langerak, Hinco J. Gierman et al. · Molecular and Cellular Biology · 2007 · 158 citations · Full text

Life Sciences, Cell Biology, Genetics +17

Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome

Andreas Jenke, Isa M. Stehle, Frank Herrmann et al. · Proceedings of the National Academy of Sciences · 2004 · 155 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

An episomal mammalian replicon: sequence‐independent binding of the origin recognition complex

Daniel Schaarschmidt, Jens Baltin, Isa M. Stehle et al. · The EMBO Journal · 2003 · 142 citations · Full text

Life Sciences, Genetics, Molecular Biology +7