Antiviral potency of adenosine analogues: Correlation with inhibition of S-adenosylhomocysteine hydrolase

( <i>S</i> )-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral Activity

Erik De Clercq, J Descamps, P. De Somer · Science · 1978 · 241 citations

Aliphatic Chain, Immunology, Molecular Biology +16

Neplanocin A. A potent inhibitor of S-adenosylhomocysteine hydrolase and of vaccinia virus multiplication in mouse L929 cells.

R. T. BORCHARDT, B T Keller, Usha Patel-Thombre · Journal of Biological Chemistry · 1984 · 184 citations · Full text

Molecular Biology, Mouse L929 Cells, Antiviral Drug +17

S-Adenosyl-L-homocysteine Hydrolase: Analogues of S-Adenosyl-L-homocysteine as Potential Inhibitors

Peter K. Chiang, Henry H. Richards, Giulio L. Cantoni · Molecular Pharmacology · 1977 · 182 citations

Carbocyclic analog of 3-deazaadenosine: a novel antiviral agent using S-adenosylhomocysteine hydrolase as a pharmacological target

John A. Montgomery, S. J. CLAYTON, H. Jeanette Thomas et al. · Journal of Medicinal Chemistry · 1982 · 155 citations

S-adenosylhomocysteine Hydrolase, Medicinal Chemistry, Biochemistry +14

Adenosine analogs as substrates and inhibitors of S-adenosylhomocysteine hydrolase

Andrzej Guranowski, John A. Montgomery, Giulio L. Cantoni et al. · Biochemistry · 1981 · 155 citations

S-adenosylhomocysteine Hydrolase, Adenosine N1-oxide, Biosynthesis +9