Modelling and simulation of biological processes in BlenX

Lorenzo Dematté, Corrado Priami, Alessandro Romanel

ACM SIGMETRICS Performance Evaluation Review · 2008 · 36 citations · 19 references

Concepts

Abstract

We introduce a scalable framework built upon the BlenX language and inspired by the Beta-binders process calculus to model, simulate and analyse biological systems. We show the features of the Beta Workbench framework on a running example based on the mitogen-activated kinase pathway. We also discuss an incremental modelling process that allows us to scale up from pathway to network modelling and analysis. We finally provide a comparison with related approaches and some hints for future extensions of the framework.

References

19