Punctuated Evolution of Prostate Cancer Genomes

Sylvan C. Baca, Davide Prandi, Michael S. Lawrence, +40

Cell

Prostate Cancer GenomesTumor HeterogeneityGeneticsCancer GenomicsMolecular Genetics +5

A highly specific SpCas9 variant is identified by in vivo screening in yeast

Antonio Casini, Michele Olivieri, Gianluca Petris, +9

Nature Biotechnology

Functional GenomicsMedicineGeneticsNext-generation SequencingMolecular Biology +10

Plasma <i>AR</i> and abiraterone-resistant prostate cancer

Alessandro Romanel, Delila Gasi Tandefelt, Vincenza Conteduca, +20

Science Translational Medicine

Tumor clone dynamics in lethal prostate cancer

Suzanne Carreira, Alessandro Romanel, Jane Goodall, +14

Science Translational Medicine

Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer

Jian Carrot‐Zhang, Nyasha Chambwe, Jeffrey S. Damrauer, +24

Cancer Cell

Genetic AnalysisTumor HeterogeneityMedicineGeneticsGenetic Epidemiology +11

Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response

Himisha Beltran, Kenneth Eng, Juan Miguel Mosquera, +41

JAMA Oncology

A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

Himisha Beltran, Clara Oromendia, Daniel C. Danila, +23

Clinical Cancer Research

Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study

Vincenza Conteduca, Daniel Wetterskog, Mansour T. A. Sharabiani, +30

Annals of Oncology

Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer

Himisha Beltran, Alessandro Romanel, Vincenza Conteduca, +16

Journal of Clinical Investigation

Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function <i>ERF</i> Mutations

Franklin W. Huang, Juan Miguel Mosquera, Andrea Garofalo, +28

Cancer Discovery