Metastatic bone disease: pathogenesis and new strategies for treatment

Induction of angiogenesis during the transition from hyperplasia to neoplasia

J Folkman, Karol Watson, Donald E. Ingber et al. · Nature · 1989 · 1.9K citations

Developmental Biology, Angiogenesis, Vascular Biology +6

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

Douglas Hanahan · Nature · 1985 · 1.3K citations

Pancreatic Cancer, Transgenic Mouse Models, Pancreatic β-Cell Tumours +8

Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.

Richard E.B. Seftor, Elisabeth A. Seftor, Naohiko Koshikawa et al. · PubMed · 2001 · 370 citations

Immunology, Pathology, Cancer Biology +16

Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

Toshiyuki Yoneda, Akira Sasaki, Colin R. Dunstan et al. · Journal of Clinical Investigation · 1997 · 248 citations · Full text

Breast Oncology, Pathology, Matrix Metalloproteinase-2 +21

Methylmethacrylate as an adjunct in internal fixation of pathological fractures. Experience with three hundred and seventy-five cases

KD Harrington, F H Sim, JE Enis et al. · Journal of Bone and Joint Surgery · 1976 · 240 citations

Surgical Oncology, Surgery, Osteoporosis +17