Transcriptional activation is a key function encoded by MLL fusion partners

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

Douglas Tkachuk, Sabine Köhler, Michael L. Cleary · Cell · 1992 · 932 citations

Life Sciences, Genetics, Molecular Genetics +16

Altered Hox expression and segmental identity in Mll-mutant mice

Benjamin Yu, Jay L. Hess, Susan Horning et al. · Nature · 1995 · 880 citations

Life Sciences, Genetics, Molecular Genetics +11

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

Y Gu, Tatsuya Nakamura, Hansjüerg Alder et al. · Cell · 1992 · 834 citations

Life Sciences, Genetics, Molecular Genetics +13

Versatile retroviral vectors for potential use in gene therapy.

Robert G. Hawley, F H Lieu, A Z Fong et al. · PubMed · 1994 · 678 citations

Life Sciences, Biotechnology, Molecular Biology +15

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

S Ziemin-van der Poel, Norah R. McCabe, Heidi J. Gill et al. · Proceedings of the National Academy of Sciences · 1991 · 594 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15