Molecular characterization of an Italian series of sporadic GISTs

Kinase Mutations and Imatinib Response in Patients With Metastatic Gastrointestinal Stromal Tumor

Michael C. Heinrich, Christopher L. Corless, George D. Demetri et al. · Journal of Clinical Oncology · 2003 · 2.3K citations

Medicine, Molecular Medicine, Oncology +17

Long-Term Results From a Randomized Phase II Trial of Standard- Versus Higher-Dose Imatinib Mesylate for Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing <i>KIT</i>

Charles D. Blanke, George D. Demetri, Margaret von Mehren et al. · Journal of Clinical Oncology · 2008 · 1K citations · Full text

Medicine, Oncology, Pharmacotherapy +14

Acquired Resistance to Imatinib in Gastrointestinal Stromal Tumor Occurs Through Secondary Gene Mutation

Cristina R. Antonescu, Peter Besmer, Tianhua Guo et al. · Clinical Cancer Research · 2005 · 831 citations

Medicine, Molecular Medicine, Oncology +15

Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors

Seiichi Hirota, Akiko Ohashi, Toshirou Nishida et al. · Gastroenterology · 2003 · 666 citations

Medicine, Genetics, Oncology +14

A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential

Jerzy Lasota, Agnieszka Dansonka‐Mieszkowska, Leslie H. Sobin et al. · Laboratory Investigation · 2004 · 317 citations · Full text

Medicine, Molecular Medicine, Oncology +17