Journal of Applied Physics · 2006 · 63 citations · 13 references
DentistryOral BiologyOral Health SciencesBiomedical OpticsOral DiagnosisOral HistologyCaries DetectionCaries DiagnosisDental CariesDental ImagingOptical Coherence TomographyOptical TomographyCaries Lesion DepthCross-sectional ImagingLesion Depth AssessmentMicrostructureOptical Caries AssessmentQuantitative Optical Coherence TomographyThree-dimensional Image ReconstructionTissue Morphology Analysis
Optical coherence tomography is an imaging technology that produces high-resolution cross-sectional images of turbid media and internal microstructures including inside living tissue. In this work, three-dimensional images of a dental microstructure, that can be used to make both qualitative and quantitative assessments of oral tissue health, were obtained. It was possible to detect subclinical caries in third molar human teeth, showing that the lesion is located below the surface at 10μm with a maximum depth lesion of 50μm. A three-dimensional image was constructed confirming that it is possible to observe different planes inside the sample. It is important to notice that the optical changes induced by the carious disease in dental tissue can be readily detected by the optical coherence tomography method, before structural changes become apparent.
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Optical biopsy and imaging using optical coherence tomography
James G. Fujimoto, Mark E. Brezinski, Guillermo J. Tearney et al. · Nature Medicine · 1995 · 888 citations