Concepedia

The −A2518G Polymorphism of Monocyte Chemoattractant Protein-1 Is Associated With Crohn's Disease

Orazio Palmieri, Anna Latiano, Enrica Salvatori, Maria Rosa Valvano, Fabrizio Bossa, Tiziana Latiano, Giuseppe Corritore, L. Di Mauro, Angelo Andriulli, Vito Annesec

The American Journal of Gastroenterology · 2010 · 32 citations · 37 references

DOI

Abstract

The -A2518G polymorphism seems to be associated with CD but does not influence MCP-1 plasma levels, which in contrast are increased in UC and CD with extensive colonic involvement.

References

37

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Paul R. Burton, David Clayton, Lon R. Cardon et al. · Nature · 2007 · 9.6K citations · Full text

Genome-wide Association Study, Disease Susceptibility, Disease Etiology +9

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Jean‐Pierre Hugot, Mathias Chamaillard, Habib Zouali et al. · Nature · 2001 · 5.6K citations

Inflammation, Autoimmune Disease, Immunology +6

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Yasunori Ogura, Denise K. Bonen, Naohiro Inohara et al. · Nature · 2001 · 5K citations · Full text

Inflammation, Autoimmune Disease, Disease Mechanism +8

Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

Mark S. Silverberg, Jack Satsangi, Tariq Ahmad et al. · Canadian Journal of Gastroenterology · 2005 · 3.3K citations · Full text

Coated Oral 5-Aminosalicylic Acid Therapy for Mildly to Moderately Active Ulcerative Colitis

Kenneth W. Schroeder, William J. Tremaine, Duane M. Ilstrup · New England Journal of Medicine · 1987 · 3K citations