Increased number of primed activated CD8+CD38+CD45RO+T cells predict the decline of CD4+T cells in HIV-1-infected patients - Concepedia

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Increased number of primed activated CD8+CD38+CD45RO+T cells predict the decline of CD4+T cells in HIV-1-infected patients

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References

1996

Year

Margarita Bofill, Amanda Mocroft, Marc Lipman, Eva Medina, Nicola Borthwick, Caroline Sabin, Anthony Timms, Mark Winter, Lusia Baptista, Margaret A. Johnson,

Abstract

Percentages of activated CD8+ cells expressing CD38+ can predict the rate of decline (slope) of the CD4+ T cells. This resides in the CD45RO+ primed population. An early prediction of the CD4+ slope will allow the clinician to target treatment to those patients that are most likely to benefit.