Epidural Lipomatosis: A Complication of Corticosteroid Therapy

Abstract

Brief Reports1 January 1979Epidural Lipomatosis: A Complication of Corticosteroid TherapyDENNIS L. BUTCHER, M.D., STEVEN A. SAHN, M.D.DENNIS L. BUTCHER, M.D.Search for more papers by this author, STEVEN A. SAHN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-1-60 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe characteristic change in body habitus associated with prolonged exposure to exogenous or endogenous corticosteroids is increased fat deposits in the face, neck, and trunk. The basis for this alteration in fat distribution is not clear. In addition, a number of patients have developed fat deposits in the mediastinum and in epicardial (1-3), episternal (4), and presacral areas (5) while taking exogenous steroids. One patient with spontaneous Cushing's syndrome had mediastinal lipomatosis (3). We were unable to find a report of epidural fat deposits associated with corticosteroids. We present here a case that suggests high-dose corticosteroids may precipitate a serious...References1. BODMANCONDEMI SJ: Mediastinal widening in iatrogenic Cushing's syndrome. Ann Intern Med 67:399-403, 1967 LinkGoogle Scholar2. KOERNERSUN HD: Mediastinal lipomatosis secondary to steroid therapy. Am J Roentgenol 98:461-464, 1966 CrossrefGoogle Scholar3. PRICERIGLER JL: Widening of the mediastinum resulting from fat accumulation. Radiology 96:497-500, 1970 CrossrefMedlineGoogle Scholar4. LUCENABENNETTPIERRE GWR: "Dewlap." A corticosteroid-induced episternal fatty tumor. N Engl J Med 275:834-835, 1966 CrossrefMedlineGoogle Scholar5. SOWERBUTTS J: Some uses of presacral oxygen insufflation. J Fac Radiol (Lond) 10:201-206, 1959 CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. 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PAULL, M.D. 1 January 1979Volume 90, Issue 1Page: 60-60KeywordsAdipose tissueCorticosteroid therapyFatsSteroids Issue Published: 1 January 1979 Copyright© 1979 American College of PhysiciansPDF DownloadLoading ...