Lung retention and metabolic fate of inhaled benzo(a)pyrene associated with diesel exhaust particles

Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide

Peter Sims, P.L. Grover, Alan Swaisland et al. · Nature · 1974 · 1.1K citations

Life Sciences, Biochemistry, Metabolism +12

Polycyclic Hydrocarbons and Cancer

Rebecca G. Harvey · Elsevier eBooks · 1981 · 748 citations

Medicine, Cancer Biology, Oncology +12

Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

Alexander W. Wood, Wayne Levin, Albert Lu et al. · Journal of Biological Chemistry · 1976 · 313 citations · Full text

Life Sciences, Biochemistry, Toxicology +17

A method for the experimental induction of bronchogenic carcinoma.

Umberto Saffiotti, F Cefis, Leonard H. Kolb · PubMed · 1968 · 300 citations

Medicine, Oncology, Toxicology +15

Binding of Nenzo[ <i>a</i> ]pyrene 7,8-Diol-9,10-Epoxides to DNA, RNA, and Protein of Mouse Skin Occurs with High Stereoselectivity

Masato Koreeda, Patrick D. Moore, Peter G. Wislocki et al. · Science · 1978 · 268 citations

Pharmacy, Biochemistry, Molecular Biology +14