Experimental Biology and Medicine · 1957 · 33 citations · 0 references
MedicineBiochemistryHematologyEnzyme MechanismEnzymologyHemostasisCoagulation CascadeCoagulation PhysiologyFibrin FormationPlatelet PhysiologyThrombin GenerationThrombosisEsterase ActivityEsterase-mediated ActivationProthrombin Activation
Purified bovine prothrombin preparations may lose the property of clotting fibrinogen but retain esterase activity. It is likely that a single molecule possesses the 2 activities. When biothrombin has lost clotting activity and only esterase activity remains, it is called esterase thrombin.