Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer

Bilateral Orchiectomy with or without Flutamide for Metastatic Prostate Cancer

Mario A. Eisenberger, Brent A. Blumenstein, E. David Crawford et al. · New England Journal of Medicine · 1998 · 868 citations · Full text

Medicine, Oncology, Surgery +14

Phospholipids in liquid chromatography/mass spectrometry bioanalysis: comparison of three tandem mass spectrometric techniques for monitoring plasma phospholipids, the effect of mobile phase composition on phospholipids elution and the association of phospholipids with matrix effects

Yuanqing Xia, Mohammed Jemal · Rapid Communications in Mass Spectrometry · 2009 · 217 citations

Natural Sciences, Chemistry, Analytical Chemistry +16

Facile One-Pot Synthesis of Aromatic and Heteroaromatic Sulfonamides

Rina Pandya, Takashi Murashima, Livio Tedeschi et al. · The Journal of Organic Chemistry · 2003 · 128 citations

Natural Sciences, Chemistry, Organic Chemistry +8

Anti-Androgens with full antagonistic activity toward human prostate tumor LNCaP cells with mutated androgen receptor

Toshiyasu Ishioka, Aya Tanatani, Kazuo Nagasawa et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 100 citations · Full text

Medicine, Oncology, Pharmacology +16

A Multicenter Randomized Trial Comparing the Luteinizing Hormone-Releasing Hormone Analogue Goserelin Acetate Alone and with Flutamide in the Treatment of Advanced Prostate Cancer

C. Tyrrell, J. E. Altwein, F. Klippel et al. · The Journal of Urology · 1991 · 99 citations

Medicine, Oncology, Pharmacology +12