A Simple Disc Degeneration Model Induced by Percutaneous Needle Puncture in the Rat Tail

Abstract

: Tail disc percutaneous needle puncture is a simple method for inducing disc degeneration and the rate of degeneration is positively related to the depth of needle puncture. This model still has some limitations that should be taken into consideration when results of disc regeneration research in this model are interpreted and extrapolated to human.