Concepedia

Discovery of N-(3-((7H-purin-6-yl)thio)-4-hydroxynaphthalen-1-yl)-sulfonamide derivatives as novel protein kinase and angiogenesis inhibitors for the treatment of cancer: Synthesis and biological evaluation. Part III

Fuming Xu, Hao Xu, Xuejian Wang, Lei Zhang, Qingli Wen, Yingjie Zhang, Wenfang Xu

Bioorganic & Medicinal Chemistry · 2013 · 24 citations · 25 references

DOIFull text

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Concepts

References

25

Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib

Thomas J. Lynch, Daphne W. Bell, Raffaella Sordella et al. · New England Journal of Medicine · 2004 · 11.5K citations

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Modeling of loops in protein structures

András Fiser, Richard Kinh Gian, Andrej Šali · Protein Science · 2000 · 2.2K citations · Full text

, , +17

Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer.

Timothy M. Browder, Catherine Butterfield, Birgit M. Kräling et al. · PubMed · 2000 · 1.6K citations

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Surflex:  Fully Automatic Flexible Molecular Docking Using a Molecular Similarity-Based Search Engine

Ajay N. Jain · Journal of Medicinal Chemistry · 2003 · 1.4K citations

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ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

Stephen R. Wedge, Donald Ogilvie, Michael Dukes et al. · PubMed · 2002 · 802 citations

, , +15