Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

Life Sciences, Biochemistry, Biomolecular Modeling +16

Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

M. F. Perutz · Nature · 1970 · 2.9K citations

Life Sciences, Biochemistry, Molecular Biology +13

Crystallographic <i>R</i> Factor Refinement by Molecular Dynamics

Axel T. Brünger, John Kuriyan, Martin Karplus · Science · 1987 · 2K citations

Natural Sciences, Biophysics, Chemistry +17

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

Teri G. Boulton, Steven H. Nye, David J. Robbins et al. · Cell · 1991 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +10

A graphics model building and refinement system for macromolecules

T. Alwyn Jones · Journal of Applied Crystallography · 1978 · 1.8K citations

Life Sciences, Biochemistry, Chemistry +17