Hypothalamic‐pituitary ageing: progressive increase in FSH and LH concentrations throughout the reproductive life in regularly menstruating women*

Abstract

An increase in FSH and LH concentrations can be detected in women with regular ovulatory cycles quite early during the reproductive life. The increase in basal FSH (and later LH) may represent the earliest endocrine marker of reproductive ageing. These age-related increases in FSH and LH can be used as hormonal markers to counsel patients as to the likelihood of their reproductive potential.