Concepedia

DNA triplex-mediated inhibition of MET leads to cell death and tumor regression in hepatoma

Garima Singhal, Md Zahid Akhter, David F. Stern, S. Datta Gupta, Ankur Ahuja, Uma Sharma, N. R. Jagannathan, Moganty R. Rajeswari

Cancer Gene Therapy · 2011 · 22 citations · 40 references

Open access

Concepts

MedicineMolecular BiologyOncologyMolecular OncologyNeoplasiaOncogenesApoptosis In CancerCancer Cell SignalingCancer Cell-cell CommunicationDna Repair In CarcinogenesisHepatocellular CarcinomaMalignant NeoplasmsCell Death In CancerHepatic ApoptosisMet InhibitorsMet-targeted TherapyTriplex Dna

References

40

Molecular cloning: A laboratory manual

Prescott L. Deininger · Analytical Biochemistry · 1990 · 86.2K citations

Life Sciences, Molecular Biology, Molecular Genetics +11

Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

Brian Druker, Moshe Talpaz, Debra Resta et al. · New England Journal of Medicine · 2001 · 5.2K citations · Full text

Medicine, Oncology, Pharmacology +12

<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling

Jeffrey A. Engelman, Kreshnik Zejnullahu, Tetsuya Mitsudomi et al. · Science · 2007 · 4.5K citations · Full text

Medicine, Oncology, Pharmacology +17

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

Laura S. Schmidt, Fuh-Mei Duh, Fan Chen et al. · Nature Genetics · 1997 · 1.5K citations

Medicine, Genetics, Oncology +17

Molecular cloning of a new transforming gene from a chemically transformed human cell line

Colin S. Cooper, Morag Park, Donald G. Blair et al. · Nature · 1984 · 991 citations

Life Sciences, Molecular Biology, Molecular Genetics +11