Thermal cyclization of 1,2-dialkynylimidazoles to imidazo[1,2-a]pyridines

A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines

Kenkichi Sonogashira, Yasuo Tohda, Nobue Hagihara · Tetrahedron Letters · 1975 · 5.1K citations

Natural Sciences, Chemistry, Catalysis +11

Comprehensive natural products chemistry

Choice Reviews Online · 1999 · 1.6K citations

Natural Sciences, Biochemistry, Chemistry +13

p-Benzyne. Generation as an intermediate in a thermal isomerization reaction and trapping evidence for the 1,4-benzenediyl structure

Richard R. Jones, Robert G. Bergman · Journal of the American Chemical Society · 1972 · 669 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

Dynemicin A, a novel antibiotic with the anthraquinone and 1,5-diyn-3-ene subunit.

MASATAKA KONISHI, HIROAKI OHKUMA, Kiyoshi Matsumoto et al. · The Journal of Antibiotics · 1989 · 300 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +6

Studies on the thermal generation and reactivity of a class of (.sigma.,.pi.)-1,4-biradicals

Andrew G. Myers, Peter S. Dragovich, Elaine Y. Kuo · Journal of the American Chemical Society · 1992 · 206 citations

Natural Sciences, Chemistry, Chemical Kinetics +6