Imprinting and X chromosome counting mechanisms determine Xist expression in early mouse development

Gene Action in the X-chromosome of the Mouse (Mus musculus L.)

Mary F. Lyon · Nature · 1961 · 4K citations

Life Sciences, Genetics, Molecular Genetics +12

Completion of mouse embryogenesis requires both the maternal and paternal genomes

James McGrath, Davor Solter · Cell · 1984 · 1.6K citations · Full text

Life Sciences, Developmental Biology, Genetics +13

A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome

Carolyn J. Brown, Andrea Ballabio, James L. Rupert et al. · Nature · 1991 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +10

The human XIST gene: Analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus

Carolyn J. Brown, Brian Hendrich, Jim L. Rupert et al. · Cell · 1992 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +10

The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus

Neil Brockdorff, Alan Ashworth, Graham F. Kay et al. · Cell · 1992 · 1K citations

Life Sciences, Genetics, Molecular Genetics +7