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Publication | Open Access

In Vitro Downregulation of Matrix Metalloproteinase-9 in Rat Glial Cells by CCR5 Antagonist Maraviroc: Therapeutic Implication for HIV Brain Infection

DOIFull Paper Access

23

Citations

20

References

2011

Year

Pasqua Gramegna, Tiziana Latronico, Maria Teresa Branà, Gaetano Di Bari, Fabio Mengoni, Valeria Belvisi, Maria Teresa Mascellino, Miriam Lichtner, Vincenzo Vullo, Claudio Maria Mastroianni,
PLoS ONE

Abstract

The present in vitro study suggests that CCR5 antagonist compounds, through their ability to inhibit MMP-9 expression and levels, might have a great potential for the treatment of HIV-associated neurologic damage.

References

YearCitations

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