Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitro-derived mRNAs encoding Oct4, Sox2, Klf4 and cMyc

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Kazutoshi Takahashi, Shinya Yamanaka · Cell · 2006 · 26.2K citations · Full text

Tissue Engineering, Regenerative Medicine, Defined Factors +14

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell · 2007 · 19.9K citations

Tissue Engineering, Regenerative Medicine, Defined Factors +14

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells

Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto et al. · Science · 2007 · 10.2K citations

Tissue Engineering, Adult Stem Cell, Transplantation Medicine +18

The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells

Kaoru Mitsui, Yoshimi Tokuzawa, Hiroaki Itoh et al. · Cell · 2003 · 3.2K citations · Full text

Knockout Mouse, Homeoprotein Nanog, Induced Pluripotent Stem Cell +8

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe et al. · Nature Biotechnology · 2007 · 2.8K citations

Tissue Engineering, Regenerative Medicine, Induced Pluripotent Stem Cell +12