Concepedia

Models of torsades de pointes: Effects of FPL64176, DPI201106, dofetilide, and chromanol 293B in isolated rabbit and guinea pig hearts

Hsien C. Cheng, Josephine Incardona

Journal of Pharmacological and Toxicological Methods · 2009 · 31 citations · 29 references

DOI

Concepts

References

29

Extracellular Potassium Modulation of Drug Block of I<sub>Kr</sub>

Tao Yang, Dan M. Roden · Circulation · 1996 · 433 citations

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Increased Short-Term Variability of Repolarization Predicts <i>d</i> -Sotalol–Induced Torsades de Pointes in Dogs

Morten B. Thomsen, S. Cora Verduyn, Milan Štengl et al. · Circulation · 2004 · 364 citations · Full text

, , +17

A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG

David Rampe, Mary Louise Roy, Adrienne T. Dennis et al. · FEBS Letters · 1997 · 295 citations

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A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644.

Craig T. January, Janet Riddle, Joseph J. Salata · Circulation Research · 1988 · 245 citations

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Effects of the chromanol 293B, a selective blocker of the slow, component of the delayed rectifier K+ current, on repolarization in human and guinea pig ventricular myocytes

Ralph Bosch · Cardiovascular Research · 1998 · 227 citations · Full text

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