Testis determination requires insulin receptor family function in mice

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Jeh-Ping Liu, Julie C. Baker, Archlbald S. Perkins et al. · Cell · 1993 · 2.9K citations

Life Sciences, Developmental Biology, Genetics +16

Female development in mammals is regulated by Wnt-4 signalling

Seppo Vainio, Minna Heikkilä, Andreas Kispert et al. · Nature · 1999 · 1.3K citations

Life Sciences, Biology, Developmental Biology +14

Cryptorchidism in mice mutant for Insl3

Serge Nef, Luis F. Parada · Nature Genetics · 1999 · 742 citations

Life Sciences, Genetics, Molecular Genetics +3

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

Domenico Accili, John Drago, Eric J. Lee et al. · Nature Genetics · 1996 · 603 citations

Medicine, Endocrinology, Genetics +10

Male-to-Female Sex Reversal in Mice Lacking Fibroblast Growth Factor 9

Jennifer S. Colvin, Rebecca P. Green, Jennifer Schmahl et al. · Cell · 2001 · 592 citations · Full text

Medicine, Genetics, Molecular Genetics +11