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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

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The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure

Hans-Joachim B�hm · Journal of Computer-Aided Molecular Design · 1994 · 1K citations

Life Sciences, Biophysics, Medicinal Chemistry +16

The Structural Basis for the Action of the Antibiotics Tetracycline, Pactamycin, and Hygromycin B on the 30S Ribosomal Subunit

Ditlev E. Brodersen, William Clemons, Andrew P. Carter et al. · Cell · 2000 · 940 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17