Memórias do Instituto Oswaldo Cruz · 1995 · 25 citations · 0 references
Veterinary MedicineInfectious DiseasesPharmacologyAntimicrobial PharmacotherapyDrug InteractionsInfectious Disease PharmacotherapyAnthelmintic PharmacologyAntifungal PharmacotherapyImmunomodulatory DrugsProtozoal InfectionsProtozoan Host-parasite InteractionsProtozoan PathogenesisAntileishmanial ChemotherapyAntileishmanial TreatmentItraconazole TherapyLeishmaniasis Of The SkinLeishmaniasis PathogenesisMucocutaneous LeishmaniasisProtozoal TreatmentTreatment Of Leishmaniasis
A randomized trial of amphotericin B (AB) alone and in combination with oral itraconazole (IZ) is carried out in two groups of 10 mucocutaneous leishmaniasis patients from Bolivia and Peru. AB+IZ combination is no better than AB monotherapy, as far as efficacy and tolerability are concerned. No antagonism was detected.